Transcriptional Regulation of Rat γ-Glutamate Cysteine Ligase Catalytic Subunit Gene is Mediated through a Distal Antioxidant Response Element

Despite it being a quintessential Phase II detoxification gene, the transcriptional regulation of the rat γ-glutamate cysteine ligase catalytic subunit (GCLC) is controversial. Computer-based sequence analysis identified three putative antioxidant response elements (AREs) at positions −889 to −865 (...

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Bibliographic Details
Main Authors: Shenvi, Swapna V., Smith, Eric J., Hagen, Tory M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756302/
https://ncbi.nlm.nih.gov/pubmed/19540342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2009.06.003
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