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Regulated secretion of complement factor H by RPE and its role in RPE migration

BACKGROUND: Variants in the gene for complement factor H (CFH) have been implicated as a major risk factor for the development of age-related macular degeneration (AMD). Little is known, however, about the factors regulating local expression and secretion of CFH by retinal pigment epithelial cells (...

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Autors principals: Kim, Yeong Hoon, He, Shikun, Kase, Satoru, Kitamura, Mizuki, Ryan, Stephen J, Hinton, David R
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756295/
https://ncbi.nlm.nih.gov/pubmed/19214553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-009-1049-y
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