Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues

BACKGROUND: Proliferation and tumor differentiation captured by the genomic grade index (GGI) are important prognostic indicators in breast cancer (BC) especially for the estrogen receptor positive (ER+) disease. The aims of this study were to convert this microarray index to a qRT-PCR assay (PCR-GG...

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Bibliographic Details
Main Authors: Toussaint, Jérôme, Sieuwerts, Anieta M, Haibe-Kains, Benjamin, Desmedt, Christine, Rouas, Ghizlane, Harris, Adrian L, Larsimont, Denis, Piccart, Martine, Foekens, John A, Durbecq, Virginie, Sotiriou, Christos
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756282/
https://ncbi.nlm.nih.gov/pubmed/19744330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-424
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