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Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours

DNA methylation is the most studied epigenetic modification due to its role in regulating gene expression, and its involvement in the pathogenesis of cancer and several diseases upon aberrations in methylation. The method of choice to evaluate genome-wide methylation has been the Illumina HumanMethy...

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Podrobná bibliografie
Vydáno v:Clin Epigenetics
Hlavní autoři: Kling, Teresia, Wenger, Anna, Beck, Stephan, Carén, Helena
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379646/
https://ncbi.nlm.nih.gov/pubmed/28392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0333-7
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