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Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours

DNA methylation is the most studied epigenetic modification due to its role in regulating gene expression, and its involvement in the pathogenesis of cancer and several diseases upon aberrations in methylation. The method of choice to evaluate genome-wide methylation has been the Illumina HumanMethy...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Kling, Teresia, Wenger, Anna, Beck, Stephan, Carén, Helena
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379646/
https://ncbi.nlm.nih.gov/pubmed/28392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0333-7
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