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Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours

DNA methylation is the most studied epigenetic modification due to its role in regulating gene expression, and its involvement in the pathogenesis of cancer and several diseases upon aberrations in methylation. The method of choice to evaluate genome-wide methylation has been the Illumina HumanMethy...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Kling, Teresia, Wenger, Anna, Beck, Stephan, Carén, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379646/
https://ncbi.nlm.nih.gov/pubmed/28392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0333-7
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