Role of leukemia cell invadosome in extramedullary infiltration

Acute myelogenous leukemias (AMLs) are characterized by medullary and extramedullary invasion. We hypothesized that a supramolecular complex, the leukemia-cell invadosome, which contains certain integrins, matrix metalloproteinases (MMPs), and other as-yet unidentified proteins, is essential for tis...

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Autori principali: Stefanidakis, Michael, Karjalainen, Katja, Jaalouk, Diana E., Gahmberg, Carl G., O'Brien, Susan, Pasqualini, Renata, Arap, Wadih, Koivunen, Erkki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756207/
https://ncbi.nlm.nih.gov/pubmed/19636064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-148643
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