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AN IL-6 HAPLOTYPE ON HUMAN CHROMOSOME 7P21 CONFERS RISK FOR IMPAIRED RENAL FUNCTION IN TYPE 2 DIABETES
Human chromosome 7p21 potentially harbors a major gene for end-stage renal disease (ESRD) and variation in glomerular filtration rate. The pro-inflammatory IL-6 is a prime positional candidate gene since chronic inflammation has been implicated in diabetic nephropathy. To test this hypothesis, singl...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756185/ https://ncbi.nlm.nih.gov/pubmed/18496509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.202 |
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