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AN IL-6 HAPLOTYPE ON HUMAN CHROMOSOME 7P21 CONFERS RISK FOR IMPAIRED RENAL FUNCTION IN TYPE 2 DIABETES

Human chromosome 7p21 potentially harbors a major gene for end-stage renal disease (ESRD) and variation in glomerular filtration rate. The pro-inflammatory IL-6 is a prime positional candidate gene since chronic inflammation has been implicated in diabetic nephropathy. To test this hypothesis, singl...

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Detalhes bibliográficos
Main Authors: Ng, Daniel P.K., Nurbaya, Siti, Ye, Sandra, Krolewski, Andrzej S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756185/
https://ncbi.nlm.nih.gov/pubmed/18496509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.202
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