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Analysis of DNA haplotypes suggests a genetic predisposition to trisomy 21 associated with DNA sequences on chromosome 21.

To test the hypothesis that there is a genetic predisposition to nondisjunction and trisomy 21 associated with DNA sequences on chromosome 21, we used DNA polymorphism haplotypes for chromosomes 21 to examine the distribution of different chromosomes 21 in Down syndrome and control families from the...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Antonarakis, S E, Kittur, S D, Metaxotou, C, Watkins, P C, Patel, A S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1985
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3360
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