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The Effect of Osteoprotegerin Gene Modification on Wear Debris Induced Osteolysis in a Murine Model of Knee Prosthesis Failure
Using an in vivo adeno-associated virus (AAV)–mediated gene transfer technique, this study evaluated the therapeutic effects of an Osteoprotegerin (OPG) transgene against orthopaedic wear debris–induced osteolysis in a long-term murine model. A titanium pin was surgically implanted into proximal tib...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756144/ https://ncbi.nlm.nih.gov/pubmed/19665222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.07.032 |
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