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The Effect of Osteoprotegerin Gene Modification on Wear Debris Induced Osteolysis in a Murine Model of Knee Prosthesis Failure

Using an in vivo adeno-associated virus (AAV)–mediated gene transfer technique, this study evaluated the therapeutic effects of an Osteoprotegerin (OPG) transgene against orthopaedic wear debris–induced osteolysis in a long-term murine model. A titanium pin was surgically implanted into proximal tib...

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Библиографические подробности
Главные авторы: Zhang, Tao, Yu, Haiying, Gong, Weiming, Zhang, Laibo, Jia, Tanghong, Wooley, Paul H., Yang, Shang-You
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756144/
https://ncbi.nlm.nih.gov/pubmed/19665222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.07.032
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