CELL-BASED OSTEOPROTEGERIN THERAPY FOR DEBRIS-INDUCED ASEPTIC PROSTHETIC LOOSENING ON A MURINE MODEL

Exogenous OPG gene modification appears a therapeutic strategy for osteolytic aseptic loosening. The feasibility and efficacy of a cell-based OPG gene delivery approach were investigated using a murine model of knee prosthesis failure. A titanium pin was implanted into mouse proximal tibia to mimic...

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Autori principali: Zhang, Laibo, Jia, Tang-Hong, Chong, Alexander CM, Bai, Ling, Yu, Haiying, Gong, Weiming, Wooley, Paul H., Yang, Shang-You
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914841/
https://ncbi.nlm.nih.gov/pubmed/20428210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.64
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