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Grassystatins A–C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors that Reduce Antigen Presentation
In our efforts to explore marine cyanobacteria as a source of novel bioactive compounds we discovered a statine unit-containing linear decadepsipeptide, grassystatin A (1), which we screened against a diverse set of 59 proteases. We describe the structure determination of 1 and two natural analogs,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756064/ https://ncbi.nlm.nih.gov/pubmed/19715320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9009394 |
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