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Mitochondrial μ-calpain is not involved in the processing of apoptosis-inducing factor

Caspase-independent cell death, an important death pathway in many cells including neurons, is executed via apoptosis-inducing factor (AIF), an oxidoreductase, localized to the mitochondrial intermembrane space. AIF is processed and released from mitochondria following mitochondrial permeability tra...

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Main Authors: Joshi, Aashish, Bondada, Vimala, Geddes, James W.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756010/
https://ncbi.nlm.nih.gov/pubmed/19393648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.04.013
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