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Absence of IFN-β impairs antigen presentation capacity of splenic dendritic cells via down-regulation of Hsp70

Type I interferons (IFNs) play a key role in linking the innate and adaptive arms of the immune system. Although produced rapidly in response to pathogens, IFNs are also produced at low levels in the absence of infection. In the present study we demonstrate that constitutively produced IFNs are nece...

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Detalhes bibliográficos
Main Authors: Ziętara, Natalia, Łyszkiewicz, Marcin, Gekara, Nelson, Puchałka, Jacek, Martins Dos Santos, Vitor A.P., Hunt, Clayton R., Pandita, Tej K., Lienenklaus, Stefan, Weiss, Siegfried
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756009/
https://ncbi.nlm.nih.gov/pubmed/19581626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803214
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