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Absence of IFN-β impairs antigen presentation capacity of splenic dendritic cells via down-regulation of Hsp70
Type I interferons (IFNs) play a key role in linking the innate and adaptive arms of the immune system. Although produced rapidly in response to pathogens, IFNs are also produced at low levels in the absence of infection. In the present study we demonstrate that constitutively produced IFNs are nece...
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Главные авторы: | , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2009
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756009/ https://ncbi.nlm.nih.gov/pubmed/19581626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803214 |
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