Functional Cross-talk between β-Catenin and NFκB Signaling Pathways in Colonic Crypts of Mice in Response to Progastrin

Eitemau Tebyg

• Activation of NF-κB is required for mediating proliferative and anti-apoptotic effects of progastrin on proximal colonic crypts of mice, in vivo
  gan: Umar, Shahid, et al.
  Cyhoeddwyd: (2008)
• AnnexinA(2) mediates upregulation of NF-κ B, β-catenin, CD44 and DCAMKL+1 in response to progastrin in miceandHEK-293 cells
  gan: Sarkar, Shubhashish, et al.
  Cyhoeddwyd: (2010)
• β-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia
  gan: Sellin, Joseph H., et al.
  Cyhoeddwyd: (2008)
• Novel Changes in NF-κB Activity during Progression and Regression Phases of Hyperplasia: ROLE OF MEK, ERK, AND p38
  gan: Chandrakesan, Parthasarathy, et al.
  Cyhoeddwyd: (2010)
• Progastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem Cells
  gan: Singh, Pomila, et al.
  Cyhoeddwyd: (2012)