تحميل...

Depletion of Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 and 2 by Bcr-Abl Promotes Chronic Myelogenous Leukemia Cell Proliferation through Continuous Phosphorylation of Akt Isoforms

The constitutive activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway commonly occurs in cancers and is a crucial event in tumorigenesis. Chronic myelogenous leukemia (CML) is characterized by a reciprocal chromosomal translocation (9;22) that generates the Bcr-Abl fusion gene. The PI3...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Hirano, Isao, Nakamura, Satoki, Yokota, Daisuke, Ono, Takaaki, Shigeno, Kazuyuki, Fujisawa, Shinya, Shinjo, Kaori, Ohnishi, Kazunori
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	American Society for Biochemistry and Molecular Biology 2009
الموضوعات:	Molecular Basis of Cell and Developmental Biology
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2755940/ https://ncbi.nlm.nih.gov/pubmed/19261608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808182200
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Depletion of Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 and 2 by Bcr-Abl Promotes Chronic Myelogenous Leukemia Cell Proliferation through Continuous Phosphorylation of Akt Isoforms

مواد مشابهة