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Activated Dectin-1 Localizes to Lipid Raft Microdomains for Signaling and Activation of Phagocytosis and Cytokine Production in Dendritic Cells

Lipid rafts are plasma membrane microdomains that are enriched in cholesterol, glycosphingolipids, and glycosylphosphatidylinositol-anchored proteins and play an important role in the signaling of ITAM-bearing lymphocyte antigen receptors. Dectin-1 is a C-type lectin receptor (CLR) that recognizes β...

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Autors principals: Xu, Shengli, Huo, Jianxin, Gunawan, Merry, Su, I-Hsin, Lam, Kong-Peng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755924/
https://ncbi.nlm.nih.gov/pubmed/19525229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009076
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