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RGS16 Inhibits Breast Cancer Cell Growth by Mitigating Phosphatidylinositol 3-Kinase Signaling

Aberrant activity of the phosphatidylinositol 3-kinase (PI3K) pathway supports growth of many tumors including those of breast, lung, and prostate. Resistance of breast cancer cells to targeted chemotherapies including tyrosine kinase inhibitors (TKI) has been linked to persistent PI3K activity, whi...

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Bibliografiska uppgifter
Huvudupphovsmän: Liang, Genqing, Bansal, Geetanjali, Xie, Zhihui, Druey, Kirk M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755894/
https://ncbi.nlm.nih.gov/pubmed/19509421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028407
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