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RGS16 Inhibits Breast Cancer Cell Growth by Mitigating Phosphatidylinositol 3-Kinase Signaling

Aberrant activity of the phosphatidylinositol 3-kinase (PI3K) pathway supports growth of many tumors including those of breast, lung, and prostate. Resistance of breast cancer cells to targeted chemotherapies including tyrosine kinase inhibitors (TKI) has been linked to persistent PI3K activity, whi...

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Detalhes bibliográficos
Main Authors: Liang, Genqing, Bansal, Geetanjali, Xie, Zhihui, Druey, Kirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755894/
https://ncbi.nlm.nih.gov/pubmed/19509421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028407
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