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RGS16 Inhibits Breast Cancer Cell Growth by Mitigating Phosphatidylinositol 3-Kinase Signaling

Aberrant activity of the phosphatidylinositol 3-kinase (PI3K) pathway supports growth of many tumors including those of breast, lung, and prostate. Resistance of breast cancer cells to targeted chemotherapies including tyrosine kinase inhibitors (TKI) has been linked to persistent PI3K activity, whi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liang, Genqing, Bansal, Geetanjali, Xie, Zhihui, Druey, Kirk M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755894/
https://ncbi.nlm.nih.gov/pubmed/19509421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028407
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