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Elevated ATF4 Expression, in the Absence of Other Signals, Is Sufficient for Transcriptional Induction via CCAAT Enhancer-binding Protein-activating Transcription Factor Response Elements

Protein limitation in vivo or amino acid deprivation of cells in culture causes a signal transduction cascade consisting of activation of the kinase GCN2 (general control nonderepressible 2), phosphorylation of eukaryotic initiation factor 2, and increased synthesis of activating transcription facto...

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Detalles Bibliográficos
Main Authors: Shan, Jixiu, Örd, Daima, Örd, Tõnis, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755847/
https://ncbi.nlm.nih.gov/pubmed/19509279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011338
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