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Despite Increased ATF4 Binding at the C/EBP-ATF Composite Site following Activation of the Unfolded Protein Response, System A Transporter 2 (SNAT2) Transcription Activity Is Repressed in HepG2 Cells

The activated amino acid response (AAR) and unfolded protein response (UPR) stress signaling pathways converge at the phosphorylation of translation initiation factor eIF2α. This eIF2α modification suppresses global protein synthesis but enhances translation of selected mRNAs such as that for activa...

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書誌詳細
主要な著者: Gjymishka, Altin, Palii, Stela S., Shan, Jixiu, Kilberg, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562058/
https://ncbi.nlm.nih.gov/pubmed/18697751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803781200
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