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Oligomerization Is Crucial for the Stability and Function of Heme Oxygenase-1 in the Endoplasmic Reticulum

Heme oxygenase-1 (HO-1), a stress-inducible enzyme anchored in the endoplasmic reticulum (ER) by a single transmembrane segment (TMS) located at the C terminus, interacts with NADPH cytochrome P450 reductase and biliverdin reductase to catalyze heme degradation to biliverdin and its metabolite, bili...

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Detalhes bibliográficos
Main Authors: Hwang, Hsuan-Wen, Lee, Jay-Ron, Chou, Kuan-Yu, Suen, Ching-Shu, Hwang, Ming-Jing, Chen, Chinpan, Shieh, Ru-Chi, Chau, Lee-Young
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755675/
https://ncbi.nlm.nih.gov/pubmed/19556236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028001
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