Cytosine Methylation Effects on the Repair of O(6)-Methylguanines within CG Dinucleotides

O(6)-Alkyldeoxyguanine adducts induced by tobacco-specific nitrosamines are repaired by O(6)-alkylguanine DNA alkyltransferase (AGT), which transfers the O(6)-alkyl group from the damaged base to a cysteine residue within the protein. In the present study, a mass spectrometry-based approach was used...

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Detalhes bibliográficos
Main Authors: Guza, Rebecca, Ma, Linan, Fang, Qingming, Pegg, Anthony E., Tretyakova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755667/
https://ncbi.nlm.nih.gov/pubmed/19531487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000919
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