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Conformational Variants of Duplex DNA Correlated with Cytosine-rich Chromosomal Fragile Sites

We found that several major chromosomal fragile sites in human lymphomas, including the bcl-2 major breakpoint region, bcl-1 major translocation cluster, and c-Myc exon 1-intron 1 boundary, contain distinctive sequences of consecutive cytosines exhibiting a high degree of reactivity with the structu...

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Detalhes bibliográficos
Main Authors: Tsai, Albert G., Engelhart, Aaron E., Hatmal, Ma'mon M., Houston, Sabrina I., Hud, Nicholas V., Haworth, Ian S., Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652318/
https://ncbi.nlm.nih.gov/pubmed/19106104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806866200
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