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Identification of a new RNA·RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation

The enzyme telomerase is a ribonucleoprotein that has a critical role in the maintenance of stable telomeres in organisms that possess linear chromosomes. Using a recently developed single molecule fluorescence coincidence method, we have studied the RNA component of telomerase (hTR) and directly ob...

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Autores principales: Ren, Xiaojun, Gavory, Gérald, Li, Haitao, Ying, Liming, Klenerman, David, Balasubramanian, Shankar
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC275565/
https://ncbi.nlm.nih.gov/pubmed/14602909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg871
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