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Identification of a new RNA·RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation

The enzyme telomerase is a ribonucleoprotein that has a critical role in the maintenance of stable telomeres in organisms that possess linear chromosomes. Using a recently developed single molecule fluorescence coincidence method, we have studied the RNA component of telomerase (hTR) and directly ob...

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Hlavní autoři: Ren, Xiaojun, Gavory, Gérald, Li, Haitao, Ying, Liming, Klenerman, David, Balasubramanian, Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC275565/
https://ncbi.nlm.nih.gov/pubmed/14602909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg871
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