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High Resolution Melting Curve Analysis of Genomic and Whole Genome Amplified DNA

BACKGROUND: High-resolution melting curve analysis is an accurate method for mutation detection in genomic DNA. However, performance in whole genome amplified (WGA) versus genomic DNA has not been directly compared. METHODS: 23 amplicons from 9 genes were PCR amplified in 39 paired genomic and WGA s...

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Main Authors: Cho, Michael H., Ciulla, Dawn, Klanderman, Barbara J., Raby, Benjamin A., Silverman, Edwin K.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755063/
https://ncbi.nlm.nih.gov/pubmed/19042988
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