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Hierarchical Inactivation of a Synthetic Human Kinetochore by a Chromatin Modifier
We previously used a human artificial chromosome (HAC) with a synthetic kinetochore that could be targeted with chromatin modifiers fused to tetracycline repressor to show that targeting of the transcriptional repressor tTS within kinetochore chromatin disrupts kinetochore structure and function. He...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754933/ https://ncbi.nlm.nih.gov/pubmed/19656847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-06-0489 |
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