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Maternal Diabetes Causes Mitochondrial Dysfunction and Meiotic Defects in Murine Oocytes

The adverse effects of maternal diabetes on embryo development and pregnancy outcomes have recently been shown to occur as early as the one-cell zygote stage. The hypothesis of this study was that maternally inherited mitochondria in oocytes from diabetic mice are abnormal and thus responsible in pa...

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Detalhes bibliográficos
Main Authors: Wang, Qiang, Ratchford, Ann M., Chi, Maggie M.-Y., Schoeller, Erica, Frolova, Antonina, Schedl, Tim, Moley, Kelle H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754898/
https://ncbi.nlm.nih.gov/pubmed/19574447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0033
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