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High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

BACKGROUND: Maternal obesity is associated with poor outcomes across the reproductive spectrum including infertility, increased time to pregnancy, early pregnancy loss, fetal loss, congenital abnormalities and neonatal conditions. Furthermore, the proportion of reproductive-aged woman that are obese...

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Autors principals: Luzzo, Kerri M., Wang, Qiang, Purcell, Scott H., Chi, Maggie, Jimenez, Patricia T., Grindler, Natalia, Schedl, Tim, Moley, Kelle H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495769/
https://ncbi.nlm.nih.gov/pubmed/23152876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049217
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