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Polarization of Tumor-Associated Neutrophil (TAN) Phenotype by TGF-β: “N1” versus “N2” TAN
TGF-β blockade significantly slows tumor growth through many mechanisms, including activation of CD8(+) T-cells and macrophages. Here, we show that TGF-β blockade also increases neutrophil-attracting chemokines resulting in an influx of CD11b(+)/Ly6G(+) tumor-associated neutrophils (TAN) that are hy...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754404/ https://ncbi.nlm.nih.gov/pubmed/19732719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.06.017 |
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