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Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live, attenuated lentivirus

In non-human primate models of AIDS, attenuated lentiviruses provide the most reliable protection from challenge with pathogenic virus but the extent to which the vaccine virus replicates after challenge is unclear. At 7 and 14 days after vaginal challenge with pathogenic SIVmac239, plasma SIVenv RN...

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Autors principals: Stone, Mars, Ma, Zhong-Min, Genescà, Meritxell, Fritts, Linda, Blozois, Shelley, McChesney, Michael B., Miller, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754392/
https://ncbi.nlm.nih.gov/pubmed/19647847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.06.052
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