Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys

Antzeko izenburuak

• Antiviral CD8(+) T cells in the genital tract control viral replication and delay progression to AIDS after vaginal SIV challenge in rhesus macaques immunized with virulence attenuated SHIV 89.6
  nork: Genescà, M., et al.
  Argitaratua: (2009)
• Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live, attenuated lentivirus
  nork: Stone, Mars, et al.
  Argitaratua: (2009)
• Depo-Provera abrogates attenuated lentivirus-induced protection in male rhesus macaques challenged intravenously with pathogenic SIVmac239
  nork: Genescà, Meritxell, et al.
  Argitaratua: (2007)
• Live Attenuated Lentivirus Infection Elicits Polyfunctional Simian Immunodeficiency Virus Gag-Specific CD8(+) T Cells with Reduced Apoptotic Susceptibility in Rhesus Macaques that Control Virus Replication after Challenge with Pathogenic SIVmac239
  nork: Genescà, Meritxell, et al.
  Argitaratua: (2007)
• Abrogation of Attenuated Lentivirus-Induced Protection in Rhesus Macaques by Administration of Depo-Provera before Intravaginal Challenge with Simian Immunodeficiency Virus mac239
  nork: Abel, Kristina, et al.
  Argitaratua: (2004)