Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
p53 protects against cancer through its capacity to induce cell cycle arrest or apoptosis under a large variety of cellular stresses. It is not known how such diversity of signals can be integrated by a single molecule. However, the literature reveals that a common denominator in all p53-inducing st...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14609953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg579 |
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