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Nanoparticle-Delivered Multimeric Soluble CD40L DNA Combined with Toll-Like Receptor Agonists as a Treatment for Melanoma
Stimulation of CD40 or Toll-Like Receptors (TLR) has potential for tumor immunotherapy. Combinations of CD40 and TLR stimulation can be synergistic, resulting in even stronger dendritic cell (DC) and CD8+ T cell responses. To evaluate such combinations, established B16F10 melanoma tumors were inject...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754331/ https://ncbi.nlm.nih.gov/pubmed/19812695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007334 |
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