Carteriosulfonic Acids A-C, GSK-3β Inhibitors from a Carteriospongia sp

Modulators of Wnt signaling have therapeutic potential in a number of human diseases. A fractionated library from marine invertebrates was screened in a luciferase assay designed to identify modulators of Wnt signaling. A fraction from a Carteriospongia sp. sponge activated Wnt signaling and was sub...

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Hauptverfasser: McCulloch, Malcolm W. B., Bugni, Tim S., Concepcion, Gisela P., Coombs, Gary S., Harper, Mary Kay, Kaur, Simran, Mangalindan, Gina C., Mutizwa, Misha M., Veltri, Charles A., Virshup, David M., Ireland, Chris M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754322/
https://ncbi.nlm.nih.gov/pubmed/19778090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np900336f
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