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Phase I Trial of Continuous Infusion Anti-Mesothelin Recombinant Immunotoxin SS1P

PURPOSE: To conduct a Phase I trial of recombinant immunotoxin SS1P given by continuous infusion in chemoresistant solid tumors expressing mesothelin. EXPERIMENTAL DESIGN: Eligible patients had mesothelioma, ovarian, or pancreatic cancer which was recurrent or unresectable despite standard therapy,...

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Main Authors: Kreitman, Robert J., Hassan, Raffit, FitzGerald, David J., Pastan, Ira
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754261/
https://ncbi.nlm.nih.gov/pubmed/19671873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0062
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