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Mutations in the FMN Domain Modulate MCD Spectra of the Ferric Heme in the Oxygenase Domain of Inducible Nitric Oxide Synthase

[Image: see text] The NOS ouput state for NO production is a complex of the FMN-binding domain and heme domain, and thereby it faciltates the interdomain electron transfer from the FMN to the catalytic heme site. Emerging evidence suggests that interdomain FMN/heme interactions are important in form...

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Detalhes bibliográficos
Main Authors: Sempombe, Joseph, Elmore, Bradley O., Sun, Xi, Dupont, Andrea, Ghosh, Dipak K., Guillemette, J. Guy, Kirk, Martin L., Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754207/
https://ncbi.nlm.nih.gov/pubmed/19405537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902141v
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