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Hypotonicity-Induced Renin Exocytosis from Juxtaglomerular Cells Requires Aquaporin-1 and Cyclooxygenase-2
The mechanism by which extracellular hypotonicity stimulates release of renin from juxtaglomerular (JG) cells is unknown. We hypothesized that osmotically induced renin release depends on water movement through aquaporin-1 (AQP1) water channels and subsequent prostanoid formation. We recorded membra...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society of Nephrology
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754103/ https://ncbi.nlm.nih.gov/pubmed/19628672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090944 |
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