The CTLA-4 gene polymorphisms are associated with CTLA-4 protein expression levels in multiple sclerosis patients and with susceptibility to disease

Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an important molecule in the down-regulation of T-cell activation. A study was undertaken to evaluate the association of the CTLA-4 gene polymorphisms −319C/T, +49A/G, (AT)(n), CT60A/G and Jo31G/T with the levels of membrane CTLA-4 (mCTLA-4) and cytoplasm...

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Main Authors: Karabon, Lidia, Kosmaczewska, Agata, Bilinska, Malgorzata, Pawlak, Edyta, Ciszak, Lidia, Jedynak, Anna, Jonkisz, Anna, Noga, Leszek, Pokryszko-Dragan, Anna, Koszewicz, Magdalena, Frydecka, Irena
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2009
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753895/
https://ncbi.nlm.nih.gov/pubmed/19740340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03083.x
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