CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves’ disease and modulates clinical phenotype of disease

Graves’ disease, an autoimmune disease with heterogeneous symptoms including Graves’ orbitopathy, has a combined genetic/environmental background, where variations within CD28/CTLA-4/ICOS genes are considered as disease markers. Association of CD28c.17+3T>C(rs3116496), CTLA-4g.319C>T(rs5742909...

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Detalhes bibliográficos
Publicado no:Endocrine
Main Authors: Pawlak-Adamska, Edyta, Frydecka, Irena, Bolanowski, Marek, Tomkiewicz, Anna, Jonkisz, Anna, Karabon, Lidia, Partyka, Anna, Nowak, Oskar, Szalinski, Marek, Daroszewski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225215/
https://ncbi.nlm.nih.gov/pubmed/27638540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-016-1096-1
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