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Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein

During replication, hepatitis C virus (HCV) NS4B protein rearranges intracellular membranes to form foci, or the web, the putative site for HCV replication. To understand the role of the C terminal domain (CTD) in NS4B function, mutations were introduced into NS4B alone or in the context of HCV poly...

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Detalhes bibliográficos
Main Authors: Aligo, Jason, Jia, Shuaizheng, Manna, David, Konan, Kouacou V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753766/
https://ncbi.nlm.nih.gov/pubmed/19703698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.07.033
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