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Complement Modulates Pathogenesis and Antibody-Dependent Neutralization of West Nile Virus Infection Through a C5-Independent Mechanism

Although the interactions of complement and viruses have been widely studied, the function of C5 and the membrane attack complex in the context of viral infection or antibody-mediated neutralization remains controversial. Using C5-depleted or deficient human or mouse sera we show that C5 does not co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mehlhop, Erin, Fuchs, Anja, Engle, Michael, Diamond, Michael S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753729/
https://ncbi.nlm.nih.gov/pubmed/19744691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.08.019
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