Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes

In this study we probe and verify the concept of designing unreactive bioactive metal complexes, in which the metal possesses a purely structural function, by investigating the consequences of replacing ruthenium in a bioactive half-sandwich kinase inhibitor scaffold by its heavier congener osmium....

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Main Authors: Maksimoska, Jasna, Williams, Douglas S., Atilla-Gokcumen, G. Ekin, Smalley, Keiran S. M., Carroll, Patrick J., Webster, Richard D., Filippakopoulos, Panagis, Knapp, Stefan, Herlyn, Meenhard, Meggers, Eric
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753370/
https://ncbi.nlm.nih.gov/pubmed/18425743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200800294
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