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In vivo roles of CDC25 phosphatases: Biological insight into the anti-cancer therapeutic targets
CDC25 phosphatases are not only rate-limiting activators of cyclin-dependent kinases (CDKs) but also important targets of the CHK1/CHK2-mediated checkpoint pathway. Each isoform of the mammalian CDC25 famiy seems to exert unique biological functions. CDC25A is a critical regulator for both G1-S and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753225/ https://ncbi.nlm.nih.gov/pubmed/19075565 |
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