The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice

STAF [Sec (selenocysteine) tRNA gene transcription activating factor] is a transcription activating factor for a number of RNA Pol III- and RNA Pol II-dependent genes including the Trsp [Sec tRNA gene], which in turn controls the expression of all selenoproteins. Here, the role of STAF in regulating...

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Auteurs principaux: CARLSON, Bradley A., SCHWEIZER, Ulrich, PERELLA, Christine, SHRIMALI, Rajeev K., FEIGENBAUM, Lionel, SHEN, Liya, SPERANSKY, Svetlana, FLOSS, Thomas, JEONG, Soon-Jeong, WATTS, Jennifer, HOFFMANN, Victoria, COMBS, Gerald F., GLADYSHEV, Vadim N., HATFIELD, Dolph
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752860/
https://ncbi.nlm.nih.gov/pubmed/18973473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081304
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