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Normalization of peak intensities in bottom-up MS-based proteomics using singular value decomposition
Motivation: LC-MS allows for the identification and quantification of proteins from biological samples. As with any high-throughput technology, systematic biases are often observed in LC-MS data, making normalization an important preprocessing step. Normalization models need to be flexible enough to...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752608/ https://ncbi.nlm.nih.gov/pubmed/19602524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp426 |
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