A statistical framework for protein quantitation in bottom-up MS-based proteomics

Motivation: Quantitative mass spectrometry-based proteomics requires protein-level estimates and associated confidence measures. Challenges include the presence of low quality or incorrectly identified peptides and informative missingness. Furthermore, models are required for rolling peptide-level i...

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Detalhes bibliográficos
Main Authors: Karpievitch, Yuliya, Stanley, Jeff, Taverner, Thomas, Huang, Jianhua, Adkins, Joshua N., Ansong, Charles, Heffron, Fred, Metz, Thomas O., Qian, Wei-Jun, Yoon, Hyunjin, Smith, Richard D., Dabney, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723007/
https://ncbi.nlm.nih.gov/pubmed/19535538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp362
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