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Bortezomib Pre-Treatment Prolongs Interferon-alpha Induced STAT1 Phosphorylation in Melanoma Cells
Bortezomib is a proteasome inhibitor that can synergize with interferon-alpha (IFN-α) to induce apoptosis in melanoma cells in vitro and inhibit tumor growth in vivo. We hypothesized that proteasome inhibition may be an effective means to sensitize melanoma cells to the direct effects of IFN-α. Pre-...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752480/ https://ncbi.nlm.nih.gov/pubmed/19396596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0710-y |
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