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A Phase I trial of Bortezomib and Interferon Alfa-2B in Metastatic Melanoma
The possibility that cytokine administration could enhance the anti-tumor effects of proteasome inhibition was explored. It was found that co-administration of bortezomib and interferon-α (IFN-α) induced synergistic apoptosis in human melanoma cell lines and prolonged survival in a murine model of m...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174542/ https://ncbi.nlm.nih.gov/pubmed/24316557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000009 |
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