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Two-site Phosphorylation of EPRS Coordinates Multimodal Regulation of Noncanonical Translational Control Activity

Glutamyl-prolyl tRNA synthetase (EPRS) is a component of the heterotetrameric GAIT (Gamma-interferon Activated Inhibitor of Translation) complex that binds 3′UTR GAIT elements in multiple interferon-gamma (IFN-γ)-inducible mRNAs and suppresses their translation. Here we elucidate the specific EPRS p...

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Detalhes bibliográficos
Main Authors: Arif, Abul, Jia, Jie, Mukhopadhyay, Rupak, Willard, Belinda, Kinter, Michael, Fox, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752289/
https://ncbi.nlm.nih.gov/pubmed/19647514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.028
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